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Disposable Pipette EXtraction (DPX)

DPX is based on unique and patented SPE devices: Pipette tips that incorporate loosely contained sorbent material, which is mixed with the sample solution.

Turbulent air bubble mixing creates a suspension of sorbent-in-the-sample ensuring optimal contact and highly efficient extraction. The extraction is performed much faster than with traditional SPE techniques.

DPX is SPE extraction in seconds instead of minutes and is used for a wide range of applications such as drugs of abuse, therapeutic drug monitoring, comprehensive screening, pharmacology studies (NNK), as well as pesticides in fruit and vegetables.

The Disposable Pipette Extraction DPX technique was developed by Professor William E. Brewer, Ph.D. from the University of Southern Carolina. Professor Brewer is the Owner-President of DPX Labs.

The DPX technique has been automated by GERSTEL using the MultiPurpose Sampler MPS.

Automated Disposable Pipette Extraction DPX offers:

  • No cross-contamination, all sample prep is done in a disposable pipette tip
  • Fast Extraction: Equilibration and elution occur in seconds
  • Low detection limits: Less than 250 µl liquid sample like blood or urine required to reach very low detection limits when combined with large volume injection
  • Excellent reproducibility and accuracy
  • Complete automation including added sample preparation steps and GC/MS or LC/MS analysis

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